As an aid in the treatment of separation-related disorders in dogs manifested by destruction & inappropriate elimination (defecation & urination) & only in combination with behavioural modification techniques. Known hypersensitivity to clomipramine & related tricyclic antidepressants. Do not use in male breeding dogs. Warnings Clomicalm may very rarely cause vomiting, changes in appetite, lethargy or an elevation in liver enzymes, which is reversible when the product is discontinued. Hepato-biliary disease has been reported, especially with pre-existing conditions, & concurrent administrations of drugs metabolised via the hepatic system. Vomiting may be reduced by co-administration with a small quantity of food. More Information